Oxygen Therapy in Chronic Respiratory Failure

Controlled Oxygen Therapy in Respiratory Failure.

Treatment of chronic respiratory failure in kyphoscoliosis: oxygen or ventilation?

Patients with kyposcoliosis and chronic respiratory insufficiency are treated either with home oxygen therapy or ventilation. Kyphoscoliotic patients demonstrate impaired ventilatory mechanics, consequently ventilation seems to be the treatment of choice. Yet, no randomised controlled trials (CRT) exist to prove it. Most investigators find it difficult to ethically justify a CRT. Therefore, the...

High-flow oxygen therapy in acute respiratory failure.

OBJECTIVE To compare the comfort of oxygen therapy via high-flow nasal cannula (HFNC) versus via conventional face mask in patients with acute respiratory failure. Acute respiratory failure was defined as blood oxygen saturation < 96% while receiving a fraction of inspired oxygen > or = 0.50 via face mask. METHODS Oxygen was first humidified with a bubble humidifier and delivered via face mas...

High-flow nasal cannula oxygen therapy during hypoxemic respiratory failure.

Oxygen therapy remains the first line intervention in acute hypoxemic respiratory failure. Several medical devices for oxygen therapy, which range from simple nasal cannula to non-rebreathing face masks, have been used in the management of acute hypoxemic respiratory failure.1 The choice of a specific oxygen delivery device is based on the patient’s oxygen requirements in terms of flow and desi...

Stimulants in Chronic Respiratory Failure

The effects of slow intravenous infusion of three different respiratory stimulants (dimeftine, nikethamide and prethcamide) on minute and alveolar ventilation, blood gases and pH were studied in 18 patients with chronic pulmonary emphysema and chronic respiratory failure. For a more accurate assessment of the results of the double blind controlled trial, a factorial design in a Youden square sc...